This article delves into the important role and significant advantages of vacuum planetary centrifugal mixers in modern industrial production. This device provides efficient and pure mixing experience for many industries with its unique vacuum function, advanced planetary mixing design, wide material adaptability, and flexible mixing capacity. The excellent performance and broad application prospects of vacuum planetary centrifugal mixers in practical production were demonstrated through two specific cases - the mixing of epoxy resin and alumina powder, and the mixing application in coating production lines. Whether in industries such as chemical, coatings, pharmaceuticals, or food, vacuum planetary centrifugal mixers can ensure uniform mixing of materials, effectively remove bubbles, and improve product quality and production efficiency. Therefore, it has become an indispensable mixing equipment in modern industrial production. Choosing a vacuum planetary centrifugal mixer will undoubtedly bring higher efficiency and stability to the production of enterprises.